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2021 Mercedes-Benz E-Class E 350

All Mercedes-Benz E-Class W213 trims (2017–2023) → All Mercedes-Benz E-Class generations →
2021 Mercedes-Benz E-Class – front Unverified
Photo: Mercedes-Benz W213 FL E 350 4MATIC AMG Line Obsidian Black Metallic (22) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
Photos show the W213/C238/A238 (facelift) (W213, 2017–2023); trim, color, and model year may differ.
All photo credits
  1. Photo: Mercedes-Benz W213 FL E 350 4MATIC AMG Line Obsidian Black Metallic (22) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
  2. Photo: Mercedes-Benz W213 FL E 350 4MATIC AMG Line Obsidian Black Metallic (21) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
  3. Photo: 2022 Mercedes E200 AMG LINE MHEV Auto by Calreyn88, CC BY-SA 4.0, via Wikimedia Commons
  4. Photo: Mercedes-Benz E350eL (rear), November 4, 2024 by メイド理世, CC BY-SA 4.0, via Wikimedia Commons
  5. Photo: Mercedes-Benz E 200 Sports (W213) interior by Tokumeigakarinoaoshima, CC BY-SA 4.0, via Wikimedia Commons

The 2021 Mercedes-Benz E-Class E 350 is a 255-hp 2.0-liter turbocharged inline-4 with a 9g-tronic 9-speed automatic and rear-wheel drive. It starts at $54,250 MSRP and is rated at 25 mpg combined.

It makes 255 horsepower at 5,800 rpm and 273 lb-ft of torque at 1800-4000 rpm, spinning to a 6,500 rpm redline. EPA fuel-economy estimates are 22 mpg city and 31 mpg highway (25 mpg combined).

The E-Class measures 194.3 inches long on a 115.7-inch wheelbase and has a curb weight of 3,781 lb.

Spec Value
Vehicle
Body TypeSedan
PowertrainGas
Price
MSRP$54,250
MSRP with Destination$55,300
Destination Charge$1,050
Engine
Engine Type2.0L Inline-4 Turbo
Displacement2 L
Horsepower255 hp @ 5,800 rpm
Torque273 lb-ft @ 1800-4000 rpm
Redline6,500 rpm
ValvetrainDOHC, 4-valves per cylinder
Bore and Stroke83.0 x 91.9
Compression Ratio10.5:1
Drivetrain
Drive TypeRear-Wheel Drive
Transmission
Transmission9G-TRONIC 9-Speed Automatic
1st Gear5.31 (34 mph **)
2nd Gear3.24 (56 mph **)
3rd Gear2.25 (81 mph **)
4th Gear1.64 (112 mph **)
5th Gear1.21 (151 mph **)
6th Gear1 (183 mph **)
7th Gear0.87 (210 mph **)
8th Gear0.72 (254 mph **)
9th Gear0.6 (305 mph **)
Reverse4.79
Final Drive2.82
Fuel Economy
City22 MPG
Highway31 MPG
Combined25 MPG
Tank Capacity17.4 gal
Suspension
Front SuspensionIndependent multi-link with coil spring, single-tube shock absorber with SSD and tubular torsion bar
Rear SuspensionIndependent multi-link with coil spring, single-tube shock absorber with SSD and tubular torsion bar
Tires & Wheels
Wheels Front8 x 18 (Cast)
Wheels Rear8 x 18 (Cast)
Tires Front245/45 R18
Tires Rear245/45 R18
Dimensions & Weight
Length194.3 in
Width81.3 in
Height57.8 in
Wheelbase115.7 in
Front Track63.2 in
Rear Track63.3 in
Ground Clearance3.82 in
Cargo Volume13.1 ft³
Curb Weight3,781 lbs
Interior
Headroom Front37.3 in
Headroom Rear37.6 in
Legroom Front41.7 in
Legroom Rear36.1 in
Shoulder Room Front57.8 in
Shoulder Room Rear57.1 in
** Theoretical max speed per gear at redline

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Safety & Recalls

NCAP safety ratings

Overall ★★★★★
Frontal crash ★★★★★
Side crash ★★★★★
Rollover ★★★★★ (9.7 % risk)
Tested variant: 2021 Mercedes-Benz E-Class 4 DR RWD
Other tested variants (5)
  • 2021 Mercedes-Benz E-Class 4 DR 4WD: 5 ★ overall
  • 2021 Mercedes-Benz E-Class 2DR RWD: overall not rated
  • 2021 Mercedes-Benz E-Class SW RWD: 5 ★ overall
  • 2021 Mercedes-Benz E-Class 2DR 4WD: overall not rated
  • 2021 Mercedes-Benz E-Class SW 4WD: 5 ★ overall

Recalls

No recalls on file with NHTSA for the 2021 Mercedes-Benz E-CLASS.

20 owner complaints to NHTSA for the 2021 Mercedes-Benz E-CLASS

Owner Complaints

20 owner complaints filed with NHTSA for the 2021 Mercedes-Benz E-CLASS (1 a fire). See all on nhtsa.gov

Most-cited areas
Electrical System7
Engine6
Back Over Prevention3
Power Train3
Fuel/Propulsion System2
Unknown Or Other2
A complaint can cite more than one area.
Most recent complaints
Aug 8, 2026 · Power Train
“Engine misfires, lower engine power, and a lit check engine/Malfunction Indicator Lamp. Mercedes-Benz issued an Emission Service Campaign (No. 2021070006, internal code 21P1590208) to replace…”
May 8, 2026 · Electrical System, Fuel/Propulsion System
“Vehicle: 2021 Mercedes-Benz E350 Sedan (W213) VIN: [XXX] While operating the vehicle, the diagnostic system displayed the fault code P240200 related to the Evaporative Emission Control System (EVAP)…”
Jan 4, 2026 · Power Train
“With the car only have about 15,000 miles the transmission has failed . I have seen there have been recalls of other models with similar complaints of transmission failure .”
Dec 27, 2025 · Engine
“Engine keeps having a misfire that Mercedes put a TSB out for and once the misfire happen I cause the vehicle to go in a limp mode which causes the vehicle to loose power happened to me in the…”
Jul 14, 2025 · Engine
“My 2021 Mercedes-Benz E350 (VIN [XXX] ) developed a serious engine issue involving cylinder misfire and check engine light. The dealer diagnosed it as a leaking exhaust valve on cylinder 4, related to…”

Complaints are unverified reports submitted to NHTSA by owners. They cover the whole model year, not a specific trim, and a count alone doesn't show how common a problem is.

Source: US National Highway Traffic Safety Administration (nhtsa.gov), matched as 2021 MERCEDES-BENZ E-CLASS. US-market vehicles only; data cached for up to 7 days.

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