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2010 Mercedes-Benz E-Class E350

All Mercedes-Benz E-Class W212 trims (2010–2016) → All Mercedes-Benz E-Class generations →
2010 Mercedes-Benz E-Class – front Unverified
Photo: Mercedes-Benz W212 FL E 300 4matic Avantgrade Obsidian Black Diplomatic (1) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
Photos show the W212 (W212, 2010–2016); trim, color, and model year may differ.
All photo credits
  1. Photo: Mercedes-Benz W212 FL E 300 4matic Avantgrade Obsidian Black Diplomatic (1) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
  2. Photo: Mercedes-Benz W212 E 350 grey (1) by Damian B Oh, CC BY-SA 4.0, via Wikimedia Commons
  3. Photo: Mercedes-Benz W212 E350 BlueTEC Obsidian Black 01 by Ethan Llamas, CC BY-SA 4.0, via Wikimedia Commons
  4. Photo: Mercedes-Benz E 200 Avantgarde (W 212, Facelift) – Heckansicht, 24. Oktober 2015, Münster by M 93, CC BY-SA 3.0 de, via Wikimedia Commons
  5. Photo: Mercedes-Benz W212 E 220 CDI Avantgarde 7-G-Tronic Obsidianschwarz Interieur by Thomas doerfer, CC BY-SA 3.0, via Wikimedia Commons

The 2010 Mercedes-Benz E-Class E350 is a 268-hp 3.5-liter V6 with a 7-speed automatic and rear-wheel drive. It starts at $48,600 MSRP and is rated at 21 mpg combined.

It makes 268 horsepower at 6,000 rpm and 258 lb-ft of torque at 2400-5000 rpm, spinning to a 6,000 rpm redline. EPA fuel-economy estimates are 18 mpg city and 26 mpg highway (21 mpg combined).

The E-Class measures 191.7 inches long on a 113.1-inch wheelbase and has a curb weight of 3,825 lb.

Spec Value
Vehicle
Body TypeSedan
PowertrainGas
Price
MSRP$48,600 ($72,421 *)
MSRP with Destination$49,475 ($73,725 *)
Destination Charge$875
Engine
Engine TypeV6
Displacement3.5 L
Horsepower268 hp @ 6,000 rpm
Torque258 lb-ft @ 2400-5000 rpm
Redline6,000 rpm
ValvetrainDOHC; duplex chain-driven
Bore and Stroke92.6 x 86.0
Compression Ratio10.7:1
Drivetrain
Drive TypeRWD
Transmission
Transmission7-speed automatic with Direct Select
1st Gear4.38 (34 mph **)
2nd Gear2.86 (52 mph **)
3rd Gear1.92 (78 mph **)
4th Gear1.37 (109 mph **)
5th Gear1 (149 mph **)
6th Gear0.82 (182 mph **)
7th Gear0.73 (205 mph **)
Reverse3.42
Final Drive3.07
Fuel Economy
City18 MPG
Highway26 MPG
Combined21 MPG
Suspension
Front Suspension3-link independent; coil spring; torsion bar; stabilizer bar
Rear SuspensionMulti-link; coil spring; tubular torsion bar; stabilizer bar
Brakes
Front Brake Disc12.7 in. / 322 mm ventilated
Rear Brake Disc11.8 in. / 300 mm ventilated
Tires & Wheels
Wheels Front8.0 x 17"
Wheels Rear8.0 x 17"
Tires Front245/45 R17
Tires Rear245/45 R17
Dimensions & Weight
Length191.7 in
Width75.9 in
Height57.7 in
Wheelbase113.1 in
Front Track62.2 in
Rear Track63 in
Ground Clearance4.1 in
Cargo Volume15.9 ft³
Curb Weight3,825 lbs
Interior
Headroom Front37.9 in
Headroom Rear38.2 in
Legroom Front41.3 in
Legroom Rear35.8 in
Shoulder Room Front57.8 in
Shoulder Room Rear56.9 in
* Amount adjusted for inflation to 2026 dollars
** Theoretical max speed per gear at redline

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Safety & Recalls

NCAP safety ratings

Overall Not rated
Frontal crash Not rated
Frontal – driver ★★★★★
Frontal – passenger ★★★★★
Side crash Not rated
Rollover ★★★★★ (9.9 % risk)
Tested variant: 2010 Mercedes-Benz E-Class 4-DR. w/SAB
Other tested variants (1)
  • 2010 Mercedes-Benz E-Class 2-DR. w/SAB: overall not rated

Recalls

No recalls on file with NHTSA for the 2010 Mercedes-Benz E-CLASS.

258 owner complaints to NHTSA for the 2010 Mercedes-Benz E-CLASS

Owner Complaints

258 owner complaints filed with NHTSA for the 2010 Mercedes-Benz E-CLASS (9 mention a crash, 5 an injury). See all on nhtsa.gov

Most-cited areas
Air Bags100
Suspension44
Unknown Or Other23
Fuel/Propulsion System22
Electrical System20
Engine16
A complaint can cite more than one area.
Most recent complaints
Sep 30, 2026 · Steering
“While I was driving the Issues with the steering column module (SCM) sudden loss of critical driver controls, erratic electrical behavior. It failed to communicate properly with the power steering…”
Aug 31, 2026 · Unknown Or Other
“UNKNOWN. I was vacuuming the car and it went dark. Then in the instrument cluster was a PRE-safe warning light, then a PRE-Safe functionality message. Then the car would not start or crank nothing…”
Apr 10, 2026 · Service Brakes
“I am writing to formally submit a complaint regarding my 2010 E350 (VIN # [XXX] ). I have taken great pride in owning and maintaining this vehicle, and I want to share my concerns based on my recent…”
Feb 17, 2026 · Exterior Lighting, Lane Departure
“All of sudden blind spot inoperable , turning signal to Rt. , signal goes LT. OR TURNING SIGNAL TO LT. , SIGNAL GOES To RT.”
Jan 19, 2026 · Structure, Service Brakes
“Car was found to have the rear subframe corrosion for issue. But also the brake lines were corroded very badly. They should be covered under the rear subframe extended warranty replacement. The rear…”

Complaints are unverified reports submitted to NHTSA by owners. They cover the whole model year, not a specific trim, and a count alone doesn't show how common a problem is.

Source: US National Highway Traffic Safety Administration (nhtsa.gov), matched as 2010 MERCEDES-BENZ E-CLASS. US-market vehicles only; data cached for up to 7 days.

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